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GILHUS Nils Erik

Tel.: +47 55 97 50 00

Fax: +47 55 97 51 65

e-mail: nils.e.gilhus@nevro.haukeland.no

 

Address

Institute of Neurology

Haukeland University Hospital

5021 Bergen, Norway

Research themes

Myasthenia gravis; non-AChR antibodies, association with thymus and thymoma. Peripheral neuropathies; complement and immunoglobulin receptors, CMT genes. Paraneoplastic autoimmunity; autoantibodies. Multiple sclerosis; brain lesions. Polio and post-polio. Epidemiology

Key words

Myasthenia gravis, thymus, thymoma, titin, ryanodine receptor, Fc receptors, paraneoplasia, neuropathies, multiple sclerosis, polio. Epidemiology

Methods

Cell cultures, cellular immunology, protein analyses (PAGE, IEF, Western blotting), cytokine detection systems (ELISA, Elispot, PCR), immunocytochemistry (confocal microscopy), molecular biology (Southern blotting, DNA sequencing). Epidemiology

Composition of the research group

Christian A. VEDELER

MD, Neurologist

Institute of Neurology, Univ. Of Bergen

Nils Erik GILHUS

MD, Neurologist

Institute of Neurology, Univ. Of Bergen

Johan A. AARLI

MD, Neurologist

Institute of Neurology, Univ. Of Bergen

Harald I. NYLAND

MD, Neurologist

Institute of Neurology, Univ. Of Bergen

Laurence BINDOFF

MD, Neurologist

Institute of Neurology, Univ. of Bergen

Geir Olve SKEIE

MD, Neurologist

Institute of Neurology, Univ. Of Bergen

Lars BØ

MD, Neurologist

Institute of Neurology, Univ. Of Bergen

Kjell-Morten MYHR

MD, Neurologist

Institute of Neurology, Univ. Of Bergen

Fredrik ROMI

MD, Neurologist

Institute of Neurology, Univ. Of Bergen

Elisabeth FARBU

MD, Neurologist

Institute of Neurology, Univ. Of Bergen

Tiina REKAND

MD, Neurologist

Institute of Neurology, Univ. Of Bergen

Anette STORSTEIN

MD, Neurologist

Institute of Neurology, Univ. Of Bergen

Recent publications

  1. ROMI F, BØ L, SKEIE GO, MYKING A, AARLI JA, GILHUS NE. Titin and ryanodine receptor epitopes are expressed in cortical thymoma along with co-stimulatory molecules. J Neuroimmunol 2002;128:82-9
  2. BØ L, VEDELER CA, NYLAND HI, TRAPP BD, MØRK SJ. Intracortical demyelination in multiple sclerosis is not associated with increased lymphocyte infiltration. Mult Scler 2003;9:323-31
  3. BØ L, VEDELER CA, NYLAND HI, TRAPP BD, MØRK SJ. Subpial demyelination in the cerebrl cortex of multiple sclerosis. J Neuropathol Exp Neurol 2003;62:723-32
  4. FARBU E, REKAND T, TYSNES OB, AARLI JA, GILHUS NE, VEDELER CA. GM1-antibodies in post-polio syndrome and previous paralytic polio. J Neuroimmunol 2003;139:141-4
  5. HOFF JM, DALTVEIT AK, GILHUS NE. Myasthenia gravis; consequences for pregnancy, delivery, and the newborn. Neurology 2003;61:1362-6
  6. MYHR KM, VÅGENES K, MARØY T, AARSETH J, NYLAND HI, VEDELER CA. Interleukin-10 promotor polymorphisms in patients with Guillain-Barré syndrome. J Neuroimmunol 2003;139:81-3
  7. REKAND T, MALE R, MYKING A, NYGAARD S, AARLI JA, HAARR L, LANGELAND N. Detection of viral sequences in archival spinal cords from fatal cases of poliomyelitis in 1951-1952. J Virol Meth 2003;114:91-6
  8. ROMI F, GILHUS NE, VARHAUG JA, MYKING A, AARLI JA. Disease severity and outcome in thymoma myasthenia gravis; a long-term observation study. Eur J Neurol 2003;10:701-6
  9. ROMI F, GILHUS NE, VARHAUG JE, MYKING A, AARLI JA. Thymectomy in non-thymoma early-onset myasthenia gravis in correlation with disease severity and muscle autoantibodies. Eur Neurol 2003;49:210-7
  10. SKEIE GO, MYGLAND Å, TREVES S, GILHUS NE, AARLI JA, ZORZATO F. Ryanodine receptor antibodies in myasthenia gravis; epitope mapping and effect on calcium release in vitro. Muscle Nerve 2003;27:81-9