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KARABUDAK Rana

Tel.: +90 312 3052460

Fax: +90 312 3051983

e-mail: rkbudak@hacettepe.edu.tr

rk01-k@tr.net

 

Address

Hacettepe University Medical School

Academic Hospital Rotterdam

Department of Neurology - Clinical Neuroimmunology Unit

Department of Basic Oncology - Immunology and Oncology Institute

Hacettepe University Hospitals

Ankara-Turkey

Research themes

Clinical Interests: Autoimmunity in CNS and Neuromuscular junction

Recent Research Themes: Matrix metalloproteinases, cytokine profiles in MS

Recent Clinical Research: Natalizumab-Multicenter Study Group

Key words

MS, MMP-9, MMP-2, Timp-1, ICAMS

Methods

Cell cultures (primary, lines), FACS analysis, immune electrophoresis, ELISA, immunocytochemistry, molecular biology (Northern blot, dot blot, recombinant DNA technology, RT-PCR, PCR), cytogenetic, MTT assay, stem cell cryobiology

Composition of the research group

Emin Kansu

MD, Immunology,Heamatology and Oncology

Basic Oncology Department

Dicle Guc

MD, PhD, Immunologist

Basic Oncology Department

Rana Karabudak

MD, Neurologist

Neurology Department

Asli Kurne

MD, Research Assistant

Neurology Department

Irem Cikrikci

MD, Research Assistant

Neurology Department

Hande Canpinar

Bs, MSc, Biologist

Basic Oncology Department

Lale Dogan

MD, MSc, Biochemist

Basic Oncology Department

Emre Yigitbas

MD, PhD student

Basic Oncology Department

Nejla Celik

Lab technician

Basic Oncology Department

Murat Aytekin

Lab technician

Basic Oncology Department

Berrin Ozturk

Lab technician

Basic Oncology Department

Burcin Tasbasan

Lab technician

Basic Oncology Department

Recent publications

  1. ARMUTLU K, MERIC A, KIRDI N, YAKUT E, KARABUDAK R. The effect of transcutaneous electrical nerve stimulation on spasticity in multiple sclerosis patients: a pilot study.Neurorehabil Neural Repair. 2003 Jun;17(2):79-82.

  2. KARABUDAK R, DOGULU CF, NURLU G, SIMSEK H, SAATCI I. Central nervous system demyelination in familial Mediterranean fever: is it a coincidence?Eur J Neurol. 2003 May;10(3):327-8. No abstract available.

  3. KILINC M, SAATCI-CEKIRGE I, KARABUDAK R. Serial analysis of soluble intercellular adhesion molecule-1 level in relapsing-remitting multiple sclerosis patients during IFN-beta1b treatment.J Interferon Cytokine Res. 2003 Mar;23(3):127-33.

  4. ARMUTLU K, KARABUDAK R, NURLU G. Physiotherapy approaches in the treatment of ataxic multiple sclerosis: a pilot study.Neurorehabil Neural Repair. 2001;15(3):203-11.

  5. DUNAL I, CIGDEM DOGULU F, SAYGI S, FIRAT M, RUACAN S, KARABUDAK R. Multiphasic disseminated encephalomyelitis: a 4-year follow-up.Eur Neurol. 2000;43(1):55-8.

  6. KANTARCI O, SIVA A, ERAKSOY M, KARABUDAK R, SUTLAS N, AGAOGLU J, TURAN F, OZMENOGLU M, TOGRUL E, DEMIRKIRAN M. Survival and predictors of disability in Turkish MS patients. Turkish Multiple Sclerosis Study Group (TUMSSG).Neurology. 1998 Sep;51(3):765-72.

  7. BOLAY H, KARABUDAK R, AYBAY C, CANDEMIR H, VARLI K, IMIR T, KANSU E. Alpha interferon treatment in myasthenia gravis: effects on natural killer cell activity.J Neuroimmunol. 1998 Mar 1;82(2):109-15.

  8. TOPCUOGLU MA, KARABUDAK R. Familial Mediterranean fever and multiple sclerosis.J Neurol. 1997 Aug;244(8):510-4.

  9. BOLAY H, KARABUDAK R, VARLI K, SARIBAS O. Low dose interferon-alpha is safe in patients with myasthenia gravis.J Neurol Neurosurg Psychiatry. 1997 Mar;62(3):302-3.

  10. DOGULU CF, KANSU T, KARABUDAK R. Alexia without agraphia in multiple sclerosis.J Neurol Neurosurg Psychiatry. 1996 Nov;61(5):528.

  11. BOLAY H, KARABUDAK R, TACAL T, ONOL B, SELEKLER K, SARIBAS O. Balo's concentric sclerosis. Report of two patients with magnetic resonance imaging follow-up.J Neuroimaging. 1996 Apr;6(2):98-103.

  12. KARABUDAK R, CIGER A, ERTURK I, ZILELI T. EEG and the linear skull fractures.J Neurosurg Sci. 1992 Jan-Mar;36(1):47-9.

  13. KARABUDAK R, CANER H, OZTEKIN N, OZCAN OE, ZILELI T. Thrombosis of intracranial venous sinuses: aetiology, clinical findings and prognosis of 56 patients.J Neurosurg Sci. 1990 Apr-Jun;34(2):117-21.

  14. NAMER IJ, KARABUDAK R, ZILELI T, RUACAN S, KUCUKALI T, KANSU E. Peripheral nervous system involvement in Behcet's disease. Case report and review of the literature.Eur Neurol. 1987;26(4):235-40.

  15. KARABUDAK R., REDER A. (1999). Raising issues in Multiple Sclerosis. Part I. 254-259.; In Frontiers in MSî, Vol.2. Eds. Siva A.Kesselring J., Thompson AJ.

  16. ÝÝ REDER A., KARABUDAK R. (1999). Raising issues in Multiple Sclerosis .Part II.259-272.; In Frontiers in MSî, Vol.2. Eds. Siva A.Kesselring J., Thompson AJ.